The Lakers were handed a 124-120 defeat by the Timberwolves last month and fortunes have been mixed for Luke Walton’s men.
Against the Timberwolves, the Lakers were outdone by the brilliance of Butler, who made five 3-pointers in the fourth quarter and scored 32 points.
James is likely to be joined on court by Tyson Chandler, who after leaving the Phoenix Suns, could make his debut for the Lakers.
And four-time MVP James thinks the Timberwolves will represent a tough challenge especially with the form of Butler.
“It wasn’t the three-point line that hurt us, it was the 20 offense rebounds that hurt us,” James said about Butler ahead of the NBA showdown.
“Jimmy [Butler] hit four in the fourth quarter and three of them were bombs.
“The offense rebounds allowed him to get extra possession which hurt us.”
After their 121-107 defeat to Toronto Raptors earlier this week, James admits Lakers are working hard to try and rectify their mistakes.
He added: “It’s very, very hard to make a game out of it when you start like that and expend so much energy trying to get back into it.
“You still learn from it. We’re going to watch some film and things of that nature.
“You don’t put too much into it. There are games like this in an 82-game season where you just don’t have it.
“We had it in spurts, but for 48 minutes we didn’t have it.”
When it comes to scoring defense, Lakers rank 27th in the league.
They have on average allowed the opposition 120 points per game, but have kept them under that mark in five of the past seven games.